Research Papers

Need help understanding the facts about animal experiments? There are many resources available – academic papers, systematic reviews and conference proceedings - that provide credible references as to why animals are not good models for human medicines.

The following list provides links to such items we believe can assist you.

Citation
Bailey, J. (2010). An assessment of the use of chimpanzees in hepatitis C research past, present and future: 2. Alternative replacement methods. Alternatives to laboratory animals : ATLA, 38(6), 471-494
Link:
https://crueltyfreeinternational.org/sites/default/files/Bailey_hepC_future_2_ATLA_2010.pdf
Keywords:
Animal welfare, alternatives, hepatitis C, species specificity
Record type:
Academic Paper
Citation
Bailey, J. (2011). Lessons from chimpanzee-based research on human disease: the implications of genetic differences. Alternatives to laboratory animals : ATLA, 39(6), 527-540.
Link:
http://www.atla.org.uk/category/atla39/atla39-6/
Keywords:
Ethics, species specificity, drug safety, drug effectiveness, reproducibility of results
Record type:
Academic Paper
Citation
Bailey, J. (2014). Monkey-based research on human disease: the implications of genetic differences. Alternatives to Laboratory Animals: ATLA, 42(5), 287-317.
Link:
http://www.atla.org.uk/monkey-based-research-on-human-disease-the-implications-of-genetic-differences/
Keywords:
Animal model, epigenetics, gene expression, genetics, macaque, monkeys, species specificity
Record type:
Academic Paper
Citation
Bailey, J., & Pereira, S. (2017). Advances in neuroscience imply that harmful experiments in dogs are unethical. Journal of Medical Ethics(24 July online).
Link:
http://jme.bmj.com/content/early/2017/07/23/medethics-2016-103630
Keywords:
Ethics, neuroscience
Record type:
Academic Paper,Expert Opinion
Citation
Bailey, J., & Taylor, K. (2009). The SCHER report on non-human primate research - biased and deeply flawed. Alternatives to laboratory animals : ATLA, 37(4), 427-435
Link:
https://crueltyfreeinternational.org/sites/default/files/Bailey_Taylor_SCHERprimates_Comment_ATLA_2009.pdf
Keywords:
Alternatives, ethics, legislation & jurisprudence/standards, drug evaluation, EU, primates, toxicity testing
Record type:
Academic Paper
Citation
Bailey, J., & Taylor, K. (2016). Non-human primates in neuroscience research: The case against its scientific necessity. Alternatives to Laboratory Animals - ATLA, 44(1)
Link:
https://crueltyfreeinternational.org/sites/default/files/Bailey_Taylor_primate%20neuroscience_ATLA_2016.pdf
Keywords:
Primates
Record type:
Academic Paper,Review
Citation
Bailey, J., Thew, M., & Balls, M. (2013). An analysis of the use of dogs in predicting human toxicology and drug safety. Alternatives to Laboratory Animals: ATLA, 41(5), 335-350.
Link:
http://altweb.jhsph.edu/pubs/journals/atla/41_5/41_5Bailey.pdf
Keywords:
Alternatives, dogs, drug safety, drug effectiveness
Record type:
Academic Paper
Citation
Bailey, J., Thew, M., & Balls, M. (2014). An analysis of the use of animal models in predicting human toxicology and drug safety. Alternatives to Laboratory Animals: ATLA, 42(3), 181-199.
Link:
https://crueltyfreeinternational.org/sites/default/files/Bailey_allspecies_toxicology_tox%20paper%202_ATLA_2014.pdf
Keywords:
Drug safety, preclinical research, rats, mouse, mice, rabbits, unreliable research, bias, animal model, species specificity
Record type:
Academic Paper
Citation
Bailey, J., Thew, M., & Balls, M. (2015). Predicting human drug toxicity and safety via animal tests: can any one species predict drug toxicity in any other, and do monkeys help? Alternatives to Laboratory Animals, 43(6), 393-403.
Link:
http://www.ncbi.nlm.nih.gov/pubmed/26753942
Keywords:
Bias, animal tests, dog, drug development, monkey, mouse, non-human primate, preclinical testing, rabbit, rat, toxicology
Record type:
Academic Paper,Data & Statistics
Citation
Bain, L., Posey Norris, S. M., Keren, N. I., & Stroud, C. (2017). Therapeutic development in the absence of predictive animal models of nervous system disorders: Proceedings of a workshop. Washington, DC: National Academies Press.
Link:
https://www.nap.edu/catalog/24672/therapeutic-development-in-the-absence-of-predictive-animal-models-of-nervous-system-disorders
Keywords:
alternatives to animal research, bias, evidence, nervous system
Record type:
Expert Opinion

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