Research Papers

Need help understanding the facts about animal experiments? There are many resources available – academic papers, systematic reviews and conference proceedings - that provide credible references as to why animals are not good models for human medicines.

The following list provides links to such items we believe can assist you.

Citation
Whittaker, A. L., & Howarth, G. S. (2014). Use of spontaneous behaviour measures to assess pain in laboratory rats and mice: How are we progressing? Applied Animal Behaviour Science, 151, 1-12.
Link:
http://www.appliedanimalbehaviour.com/article/S0168-1591%2813%2900259-1/abstract
Keywords:
Mouse, mice, rat, pain assessment, animal welfare, acute pain, chronic pain
Record type:
Academic Paper
Citation
Wieseler, B., Wolfram, N., McGauran, N., Kerekes, M. F., Vervölgyi, V., Kohlepp, P., et al. (2013). Completeness of reporting of patient-relevant clinical trial outcomes: Comparison of unpublished clinical study reports with publicly available data. PLoS Medicine, 10(10), e1001526.
Link:
http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001526
Keywords:
Reporting bias, publication bias
Record type:
Academic Paper
Citation
Working Group of the Oxford Centre for Animal Ethics, Linzey, A., & Linzey, C. (2015). Normalising the unthinkable: The ethics of using animals in research: Oxford Centre for Animal Ethics. Commissioned by The BUAV and Cruelty Free International.
Link:
http://www.oxfordanimalethics.com/wpcms/wp-content/uploads/Normalising-the-Unthinkable-Report.pdf
Keywords:
Ethics, animal model, unreliability, bias, 3Rs, animal ethics committees
Record type:
Report
Citation
Worth, A., Barroso, J., Bremer, S., Burton, J., Casati, S., Coecke, S., et al. (2014). Alternative methods for regulatory toxicology – a state-of-the-art review (No. Report EUR 26797 EN). Ispra (VA), Italy: European Commission. Joint Research Centre. Institute for Health and Consumer Protection. European Union Reference Laboratory for Alternatives to Animal Testing.
Link:
https://eurl-ecvam.jrc.ec.europa.eu/news/review-of-available-methods
Keywords:
3Rs, alternatives, Europe
Record type:
Government Report,Review
Citation
Yoon, D. Y., Mansukhani, N. A., Stubbs, V. C., Helenowski, I. B., Woodruff, T. K., & Kibbe, M. R. (2014). Sex bias exists in basic science and translational surgical research. Surgery, 156(3), 508-516
Link:
http://dx.doi.org/10.1016/j.surg.2014.07.001
Keywords:
Sex bias, basic science, biomedical research
Record type:
Academic Paper
Citation
Zambrano, A. (2016). Animal experimentation as a form of rescue. Between the Species, 19(1)
Link:
http://digitalcommons.calpoly.edu/bts/vol19/iss1/3/
Keywords:
Ethics
Record type:
Academic Paper
Citation
Zuang, V., Desprez, B., Barroso, J., Belz, S., Berggren, E., Bernasconi, C., et al. (2015). EURL ECVAM status report on the development, validation and regulatory acceptance of alternative methods and approaches (2015). Ispra, Italy: European Commission.
Link:
http://publications.jrc.ec.europa.eu/repository/bitstream/JRC97811/lbna27474enn.pdf
Keywords:
Alternatives, European Union, animal model
Record type:
Government Report
Citation
Zuang, V., Schäffer, M., Tuomainen, A. M., Amcoff, P., Bernasconi, C., Bremer, S., et al. (2013). EURL ECVAM progress report on the development, validation and regulatory acceptance of alternative methods (2010-2013). Prepared in the framework of Directive 76/768/EEC and Regulation (EC) No 1223/2009 on cosmetic products. Ispra (VA), Italy: Institute for Health and Consumer Protection, Joint Research Centre, European Commission.
Link:
https://eurl-ecvam.jrc.ec.europa.eu/eurl-ecvam-releases-2013-progress-report-development-validation-regulatory-acceptance-alternative-methods
Keywords:
Alternatives, validation, cosmetics, 3Rs, regulation, European Union
Record type:
Government Report
Citation
Zuang, V., Viegas Barroso, J. F., Belz, S., Berggren, E., Bernasconi, C., Bopp, S., et al. (2017). EURL ECVAM status report on the development, validation and regulatory acceptance of alternative methods and approaches (2017). Luxembourg: European Commission
Link:
http://publications.jrc.ec.europa.eu/repository/handle/JRC108831
Keywords:
EURL ECVAM, alternatives
Record type:
Government Report

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