Research Papers

Need help understanding the facts about animal experiments? There are many resources available – academic papers, systematic reviews and conference proceedings - that provide credible references as to why animals are not good models for human medicines.

The following list provides links to such items we believe can assist you.

Citation
Bakand, S. (2016). Cell culture techniques essential for toxicity testing of inhaled materials and nanomaterials in vitro Journal of Tissue Science & Engineering, 7(3).
Link:
https://www.omicsonline.org/open-access/cell-culture-techniques-essential-for-toxicity-testing-of-inhaled-materials-andnanomaterials-in-vitro-2157-7552-1000181.php?aid=81104
Keywords:
Air liquid interface, cell culture techniques, inhaled materials, in vitro, nanomaterials, nanoparticles, toxicity testing, alternatives to animal resarch
Record type:
Academic Paper,Expert Opinion
Citation
Batista, K. T., Andrade, R. R. d., & Bezerra, N. L. (2012). The role of Research Ethics Committees. O papel dos comitês de ética em pesquisa. Revista Brasileira de Cirurgia Plástica, 27, 150-155.
Link:
http://www.scielo.br/pdf/rbcp/v27n1/en_25.pdf
Keywords:
Animal ethics committees
Record type:
Academic Paper
Citation
Beauchamp, T. L., & Morton, D. B. (2015). The upper limits of pain and suffering in animal research. Cambridge Quarterly of Healthcare Ethics, 24(04), 431-447.
Link:
http://dx.doi.org/10.1017/S0963180115000092
Keywords:
Ethics, animal welfare, animal suffering,
Record type:
Academic Paper
Citation
Beery, A. K., & Zucker, I. (2011). Sex bias in neuroscience and biomedical research. Neuroscience & Biobehavioral Reviews, 35(3), 565-572
Link:
http://www.sciencedirect.com/science/article/pii/S0149763410001156
Keywords:
Sex bias, nervous system diseases, estrous cycles
Record type:
Academic Paper
Citation
Bello, S., Krogsboll, L. T., Gruber, J., Zhao, Z. J., Fischer, D., & Hrobjartsson, A. (2014). Lack of blinding of outcome assessors in animal model experiments implies risk of observer bias. Journal of Clinical Epidemiology, 67(9), 973-983.
Link:
http://www.jclinepi.com/article/S0895-4356%2814%2900157-7/abstract
Keywords:
Flaws in animal research, animal model, bias
Record type:
Academic Paper
Citation
Benam, Kambez H., Novak, R., Nawroth, J., Hirano-Kobayashi, M., Ferrante, Thomas C., Choe, Y., et al. (2016). Matched-comparative modeling of normal and diseased human airway responses using a microengineered breathing lung chip. Cell Systems, 3(5), 456–466.
Link:
http://dx.doi.org/10.1016/j.cels.2016.10.003
Keywords:
Alternatives to animal research, organ chip, microfluidic, cigarette smoke, electronic cigarette, lung airway, cell culture, cilia, human study, transcriptomic analysis, cytokine, biomarker
Record type:
Academic Paper,Research Study
Citation
Ben-David, U., Ha, G., Tseng, Y.-Y., Greenwald, N. F., Oh, C., Shih, J., et al. (2017). Patient-derived xenografts undergo mouse-specific tumor evolution. Nature Genetics, 49, 1567-1575
Link:
http://dx.doi.org/10.1038/ng.3967
Keywords:
Bias, cancer, mouse, mice
Record type:
Academic Paper,Research Study
Citation
Berns, G. S., Brooks, A. M., & Spivak, M. (2012). Functional MRI in awake unrestrained dogs. PLoS ONE, 7(5), e38027. doi: 10.1371/journal.pone.0038027.
Link:
http://dx.doi.org/10.1371%2Fjournal.pone.0038027
Keywords:
Dogs
Record type:
Academic Paper,Research Study
Citation
Blundell, C., Tess, E. R., Schanzer, A. S. R., Coutifaris, C., Su, E. J., Parry, S., et al. (2016). A microphysiological model of the human placental barrier. Lab on a Chip, 16(16), 3065-3073
Link:
http://dx.doi.org/10.1039/C6LC00259E
Keywords:
Alternative to animal research, placenta on a chip
Record type:
Research Study
Citation
Bopp, S., Berggren, E., Kienzler, A., van der Linden, S., & Worth, A. (2015). Scientific methodologies for the assessment of combined effects of chemicals – a survey and literature review. Use of novel and alternative methods in the assessment of effects from combined exposure to multiple chemicals (JRC Technical Reports): European Commission, European Union.
Link:
http://bookshop.europa.eu/is-bin/INTERSHOP.enfinity/WFS/EU-Bookshop-Site/en_GB/-/EUR/ViewPublication-Start?PublicationKey=LBNA27471
Keywords:
Alternatives, toxicology, public health
Record type:
Government Report

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