Research Papers

Need help understanding the facts about animal experiments? There are many resources available – academic papers, systematic reviews and conference proceedings - that provide credible references as to why animals are not good models for human medicines.

The following list provides links to such items we believe can assist you.

Citation
Bottini, A. A., & Hartung, T. (2009). Food for thought... on the economics of animal testing. ALTEX, 26(1), 3-16.
Link:
http://www.altex.ch/Current-issue.50.html?iid=104&aid=1
Keywords:
Economics, alternatives, food industry, drug industry, cosmetics industry
Record type:
Academic Paper,Expert Opinion
Citation
Bowen, A., & Casadevall, A. (2015). Increasing disparities between resource inputs and outcomes, as measured by certain health deliverables, in biomedical research. Proceedings of the National Academy of Sciences, 112(36), 11335–11340.
Link:
http://www.pnas.org/content/112/36/11335.abstract
Keywords:
Research efficiency
Record type:
Academic Paper
Citation
Brinks, V., Jiskoot, W., & Schellekens, H. (2011). Immunogenicity of therapeutic proteins: The use of animal models. Pharmaceutical Research, 28(10), 2379-2385.
Link:
http://dx.doi.org/10.1007/s11095-011-0523-5
Keywords:
Animal models, bias, immunogenicity, therapeutic proteins
Record type:
Academic Paper,Review
Citation
Burden, N., Sewell, F., & Chapman, K. (2015). Testing chemical safety: What is needed to ensure the widespread application of non-animal approaches? PLoS Biology, 13(5), e1002156.
Link:
http://dx.doi.org/10.1371%2Fjournal.pbio.1002156
Keywords:
alternatives, regulation, validation
Record type:
Academic Paper
Citation
Carninci, P. (2014). Genomics: Mice in the ENCODE spotlight. Nature, 515(7527), 346-347.
Link:
http://www.nature.com/nature/journal/v515/n7527/full/515346a.html
Keywords:
Mouse, mice, genome regulation
Record type:
Research Study
Citation
Cesarovic, N., Arras, M., & Jirkof, P. (2014). Impact of inhalation anaesthesia, surgery and analgesic treatment on home cage behaviour in laboratory mice. Applied Animal Behaviour Science, 157, 137-145.
Link:
http://www.sciencedirect.com/science/article/pii/S0168159114001130
Keywords:
Mice, mouse, animal welfare, anaesthesia
Record type:
Academic Paper,Research Study
Citation
Chandrasekera, P. C., & Pippin, J. J. (2013). Of rodents and men: Species-specific glucose regulation and Type 2 diabetes research. ALTEX.
Link:
http://www.altex.ch/resources/Chandrasekera_epub.pdf
Keywords:
Mouse, mice, type 2 diabetes, evidence bias
Record type:
Academic Paper
Citation
Chandrasekera, P. C., & Pippin, J. J. (2015). The human subject: an integrative animal model for 21st century heart failure research. American Journal of Translational Research, 7(9), 1636-1647.
Link:
http://www.ajtr.org/files/ajtr0012548.pdf
Keywords:
Heart failure, animal models, translatability, human relevance, human-based research
Record type:
Academic Paper,Review
Citation
COACH. (2014). Towards the replacement of in vivo repeated dose systemic toxicity testing. SEURAT-1 Annual Report, Vol. 4: European Commission Research & Innovation, Cosmetics Europe.
Link:
http://www.seurat-1.eu/pages/library/seurat-1-annual-report.php
Keywords:
Toxicity testing, drug safety, cosmetics, alternatives
Record type:
Government Report
Citation
Coghlan, S. (2014). Recognizing nonhuman morality. Between the Species, 17(1).
Link:
http://digitalcommons.calpoly.edu/bts/vol17/iss1/5/
Keywords:
Ethics, morality
Record type:
Academic Paper

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