Key Research Articles

Need help understanding the facts about animal experiments? There are many resources available – academic papers, systematic reviews and conference proceedings – that provide credible references as to why animals are not good models for human medicine.

The following list provides links to such items we believe can assist you.

TITLE: Are researchers moving away from animal models as a result of poor clinical translation in the field of stroke? An analysis of opinion papers

AUTHORS: Pandora Pound and Rebecca Ram

PUBLICATION: British Medical Journal

YEAR: 2020

LINK: https://openscience.bmj.com/content/4/1/e100041

TITLE:  From Mice to Monkeys? Beyond Orthodox Approaches to the Ethics of Animal Model Choice

AUTHORS: Rebecca L. Walker and Matthias Eggel

PUBLICATION:  Animals 2020

YEAR: 2020

LINK: https://www.mdpi.com/2076-2615/10/1/77/htm

TITLE:  The Relevance of In Silico, In Vitro and Non-human Primate Based Approaches to Clinical Research on Major Depressive Disorder

AUTHORS:Constanc¸a Carvalho et al

PUBLICATION: Alternatives to Laboratory Animals 

YEAR: 2019

LINK:https://journals.sagepub.com/doi/pdf/10.1177/0261192919885578 

TITLE:  Opinion Versus Evidence for the Need to Move Away from Animal Testing

AUTHOR:  Thomas Hartung

PUBLICATION: ALTEX

YEAR: 2017

LINK: https://www.researchgate.net/publication/315881174_Opinion_versus_evidence_for_the_need_to_move_away_from_animal_testing

TITLE: Inappropriate modeling of chronic and complex disorders: How to reconsider the approach in the context of predictive, preventive and personalized medicine, and translational medicine

AUTHORS: Soroush Seifirad and Vahid Haghpanah 

PUBLICATION: EMPA Journal 

YEAR: 2019

LINK: https://link.springer.com/article/10.1007/s13167-019-00176-z

 

 

TITLE: Is it Time for Reviewer 3 to Request Human Organ Chip Experiments Instead of Animal Validation Studies

AUTHORS: Donald E Ingber

PUBLICATION: Advanced Science 

YEAR: 2020

LINK: https://onlinelibrary.wiley.com/doi/10.1002/advs.202002030

TITLE:   Alzheimer’s Disease, and Breast and Prostate Cancer Research: Translational Failures and the Importance to Monitor Outputs and Impact of Funded Research

AUTHORS: Francesca Pistollato et al 

PUBLICATION: Animals 2020 

YEAR: 2020

LINK:  https://www.mdpi.com/2076-2615/10/7/1194

TITLE: Why are Validated Alternatives Not Being used to Replace Animal Tests?

AUTHORS: Michael Balls

PUBLICATION:  Alternatives to Laboratory Animals

YEAR: 2018

LINK:  https://journals.sagepub.com/doi/abs/10.1177/026119291804600105

TITLE: Modeling the Human Bone–Tumor Niche: Reducing and Replacing the Need for Animal Data

AUTHORS: Srinivasa R Rao et al

PUBLICATION: JBMR PLUS

YEAR: 2020

LINK: https://asbmr.onlinelibrary.wiley.com/doi/epdf/10.1002/jbm4.10356  

TITLE: Australian Regulation of Animal Use in Science and Education: A Critical Appraisal

AUTHORS: Aaron C Timoshanko, Helen Marston, Brett A Lidbury

PUBLICATION: Institute for Laboratory Animal Research (ILAR)

YEAR: 2016

LINK: https://academic.oup.com/ilarjournal/article/57/3/324/3796585

TITLE: Some Reasons Why Preclinical Studies of Psychiatric Disorders Fail to
Translate: What Can Be Rescued from the Misunderstanding and Misuse of Animal ‘Models’?

AUTHORS: Clare Stanford 

PUBLICATION: Alternatives to Laboratory Animals 

YEAR: 2020

LINK: https://pubmed.ncbi.nlm.nih.gov/32777937/

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